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Despite the different doses of semaglutide and tirzepatide and timepoints studied, the results of SURMOUNT-5 and the Truveta Research study were consistent, namely that tirzepatide-based medications performed better than semaglutide-based medications: SURMOUNT-5 study : At 72 weeks, weight loss was 20.2% for Zepbound (tirzepatide AOM) compared to 13.7% for Wegovy (semaglutide AOM)
Waqas SA, Sohail MU, Saad M et al (2025) Efficacy of GLP-1 Receptor Agonists in Patients with Heart Failure and Mildly Reduced or Preserved Ejection Fraction: A Systematic Review and Meta-Analysis
Most common or mild Ozempic side effects can be easily managed at home
This delayed gastric emptying is how the medication suppresses appetite and helps with weight loss, but it can also trigger nausea, bloating, and mild stomach discomfort as your digestive system adjusts
It gives you that bouncy, juicy look we all crave
K., Patterson, R
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