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Clinical trials (STEP programme) have demonstrated that Wegovy can lead to significant weight losswith participants achieving an average of approximately 15% weight loss at 68 weeks when combined with lifestyle modifications
Skeletal and cardiac muscles that use fatty acids as a dietary fuel have high concentrations of carnitine
This is especially true of the 1.5mg starter dose, which is designed to get your body used to the medication and reduce the risk of side effects
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For patients with heart failure or chronic kidney disease, SGLT2 inhibitors are generally preferred first, with GLP-1 agonists considered when SGLT2 inhibitors are contraindicated or not tolerated
It is also not recommended for patients with severe gastrointestinal disease, including severe gastroparesis
