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When you feel nauseous, you tend to reach for bland foods like rice and toast foods that tend to be low in fiber

Because these medications work in part by slowing how quickly food leaves the stomach, the most frequent GLP-1 side effects are gastrointestinal symptoms, such as: Nausea Vomiting Diarrhea Constipation Upset stomach or heartburn These symptoms are usually most pronounced during the first few weeks of treatment or after a dose increase

Nausea can be mitigated by eating more slowly, eating regular smaller meals, avoiding spicy, fried or greasy foods and drinking cold water

This may involve a key are of the brain reward circuit, the ventral striatum, with experimenters showing if they directly administer GLP-1 agonists into this region, rats show reduced craving for oxycodone or cocaine, possibly through reducing drug-induced dopamine release

Preservatives or Vitamins Some GLP-1 medications include preservatives or vitamins that can cause mild localized reactions in certain individuals

These medications mimic the glucagon-like peptide-1 hormone, which helps regulate blood sugar and appetite