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The mutant achieved 3.1-fold higher ATP-generating activity and 1.7-fold higher GSH productivity compared with the control strain

A practical approach to the unexpectedly elevated result A practical workup starts with the report, exposure history, prior results, and baseline labs, and moves to repeat testing or referral as the findings warrant

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Mechanistically, it activates Nrf2 and its nuclear translocation, thereby enhancing the expression of downstream antioxidant genes to relieve oxidative stress