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This was compared to 4.6% in the placebo group

In the STEP 1 semaglutide trial (Wilding et al., NEJM , 2021) and the SURMOUNT-1 tirzepatide trial (Jastreboff et al., NEJM , 2022), nausea affected roughly 44% of semaglutide patients and about 24% of tirzepatide patients at the maximum dose

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The search also included abstracts published in the last American Diabetes Association (ADA) Scientific Sessions

Participants who received semaglutide showed slower aging patterns across several epigenetic clocks tied to inflammation and major organ systems, including the heart, brain, kidneys, liver and metabolic system