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This is the treatment-policy estimand consistent with the intention-to-treat principle, counting everyone regardless of whether they stayed on drug
Not suitable for everyone, particularly those with heart conditions or high blood pressure
Following IPTW adjustment, the final cohorts consisted of 416 patients in the semaglutide OW cohort and 1093 in the SGLT2i cohort (empagliflozin, 63.9%
Insert the needle and press the button until the dose counter shows 0
Downstream processing, including gentle harvesting (centrifugation or filtration) and freeze-drying, preserves therapeutic compounds but increases costs (50100/kg), while advanced extraction (chromatography, ultrafiltration) further elevate expenses but yield high-value extracts (phycocyanin at 100500/g) (Gao et al
