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Researchers often call this investigational pairing CagriSema. Studies have examined it for effects on appetite, energy intake, body weight, and metabolic control in adults with overweight or obesity, including some populations with type 2 diabetes

Trials have examined its effects on biologic pathways related to energy balance compared with placebo and other agents in controlled research settings

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But the high sodium load and the risk of metabolic alkalosis (if overused) are real

doi: 10.26355/eurrev_201908_18635 224 WeiHWuQShiYLuoALinSFengXet al