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Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

Studied in models involving amylin receptor signaling, appetite-related pathways, and metabolic response

Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate