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Both the FDA and the European Medicines Agency are also now considering the approval of semaglutide for the treatment of chronic kidney diseases in patients with type 2 diabetes (Manalac, June 2024
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These outcomes lead to the remodeling of the extracellular matrix, oxidative stress, inflammation, cardiomyocyte apoptosis, fibrosis, and metabolic abnormalities [55]
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The effect of tirzepatide was compared to wild-type obese and GLP- 1 receptor-null mice to determine whether GIP receptor agonism plays a role
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