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References Standing Committee on the Scientific Evaluation of Dietary Reference Intakes - Panel on Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids and the Subcommittee on Upper Reference Levels of Nutrients, Food and Nutrition Board, Institute of Medicine (IOM)

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This decline increases oxidative stress, which may impact teenagers experiencing significant physical and emotional changes

Deficiencies in the urea cycle can cause arginine to become conditionally essential