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Pathways related to immunoglobulin, production, defense responses and B cell activation were among those downregulated, including immunoglobulin production ( IGKV112 , IGKV117 ), adaptive immune response (for example, CX3CR1 , FCGR1BP ) and B cell activation ( HDAC9 , CD180 , MNDA ) (Extended Data Fig

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These are mechanistic findings, not proven human therapeutic effects

An analysis of two 12-week randomized sham CPAP-controlled trials

UMUC-3 human CTR, AMY1R, AMY2R and AMY3R, as well as CGRP, AM1 and AM2 OE cells was established for cAMP assay validation