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This happens because semaglutide slows how quickly food moves through the stomach

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By exerting both central and peripheral metabolic regulatory effects, tirzepatide has substantially narrowed the gap between pharmacological and surgical weight loss, representing a significant milestone in the advancement of multi-receptor agonist therapies for obesity [108]

However, lower levels of self-reported effectiveness among older adults and past users, as well as lower rates of use among uninsured Americans, suggest a need for further exploration of patterns of access and benefit across various subgroups