Mitochondrial cristae shape determines respiratory chain supercomplexes assembly and respiratory efficiency
Answer: Glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications that includes semaglutide (Wegovy, Ozempic, Rybelsus), tirzepatide (Zepbound, Mounjaro), liraglutide (Victoza, Saxenda), and orforglipron (Foundayo), have become increasingly popular for obesity treatment (Mehrtash, JAMA Intern Med 2025)
The effects can be experienced within the first few days, whether thats an effect on your appetite or side effects like nausea, vomiting or diarrhea. These two new drugs are part of a larger class of GLP-1 drugs that mimic the gut hormone GLP-1, which is made naturally in your intestines and brain
Some individuals report subjective improvements in energy levels, though controlled clinical trials demonstrating objective benefits are limited
This is an evolving topic as always, so Im sure itll be one well revisit again on the podcast
doi: 10.1111/j.1600-0412.2011.01325.x 73 HaigG