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Expected Weight-Loss Results Weight loss with GLP-1 medications is steady and progressive rather than sudden
Zizzari AT, Pliatsika D, Gall FM, Fischer T, Riedl R
00:06:12 Vickie Danaher So in terms of efficacy, be aware that oral orforglipron 17.2 milligram tablet daily for 72 weeks leads to about 9% more weight loss than with placebo
Researchers have suggested this may happen, but the clearest support comes from animal studies [2]
The pattern in trials has been broadly consistent with other incretin-based therapies (such as Mounjaro and Wegovy), and most side effects have been mild to moderate and dose-dependent, occurring mainly during the initial dose-escalation period
Many patients encounter a plateau around months 69 as the body adapts
