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Semaglutide works in part by increasing satiety and slowing digestion, which can mute cravings
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The role of O -linked GlcNAc modification on the glucose response of ChREBP
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In a Phase 3 clinical trial Orforglipron demonstrated superior glycaemic control compared with Dapagliflozin, with a tolerability profile consistent with the GLP-1 receptor agonist class, including increased rates of discontinuation due to adverse events, positioning it as a potential effective oral treatment option for type 2 diabetes
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