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Data obtained from a panel of in vitro receptor binding assays suggest that Metadoxine affects the Serotonin receptor family

[1] [2] Following sleeve gastrectomy, the substantial reduction in stomach volume means fewer parietal cells are available, leading to a reduction in intrinsic factor production though the degree varies between individuals and intrinsic factor production does not cease entirely

Miroshnichenko et al., 2005)

It is involved in several biochemical processes, including detoxification, immune response, and cellular repair

doi:10.1016/j.nbd.2024.106711 122

These trials are of low quality, and as such, use in widespread clinical practice is premature