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Although Th2-associated cytokines, such as IL-4 and IL-13, may promote fibrogenic responses, the overall contribution of Th2 cells to MASH is still inconclusive (127, 128) ( Figure 6A )

Hashimotos is the most common cause of hypothyroidism, particularly in women, and is often associated with a range of symptoms such as fatigue, weight gain, depression, and sensitivity to cold

R.Boughton-SmithN

Because it relies on the pituitary's own machinery, the GH release it produces follows the body's natural pulsing rhythm rather than overriding it