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News Article Infographic: The rise of NHS GLP-1 drug prescription 28 November 2025 This graph below shows the prescription of GLP-1 medications from shortly after prescription medication Liraglutide was approved for NHS use in specialist weight management services in England to the present day

Through a greater reliance on fat for energy, the body reduces depletion of muscle glycogen

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Therefore, it is contraindicated in patients with a history of thromboembolic disease, active or serious infection, and severe liver impairment