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Lelubre, C
The GLP-1 receptor activation reduces appetite through direct signaling to the hypothalamus, slows gastric emptying so food stays in the stomach longer, and enhances insulin secretion
In the brain of a person who binge-eats, the reward or incentive salience of food is often hyper-amplified
This delayed transit helps patients feel fuller for longer, contributing to reduced calorie intake and weight loss
A randomized controlled trial of dietary improvement for adults with major depression (the SMILES trial)
Hormone replacement therapy and GLP-1 receptor agonists target completely different systems in the body
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