Newer delivery methods under development include GLP-1 transdermal patches , which would bypass injection entirely, and oral tirzepatide formulations
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Another conceivable mechanism is that long-term treatment with GLP-1 RA could mitigate the effect of postprandial endogenous GLP-1 [30, 31]
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Figure 1 also includes DMF filings, which are not necessary for bulk manufacturing but can be useful for promotional purposes