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We often see that the effect feels clearer when you: keep track of calories avoid overeating choose smaller but more nutrient-dense portions keep a stable protein intake eat regularly rather than spontaneously Conversely, large meals, very unhealthy food or unstructured eating can drown out the medication for some users

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The body composition after regain was worse than before treatment began

While these cardiovascular effects appear partially mediated by weight loss, additional mechanisms may contribute