GLP-1 analogues, such as semaglutide (Wegovy), liraglutide (Ozempic), oral semaglutide (Rybelsus), retatrutide, and tirzepatide, have emerged as powerful tools in the battle against obesity and diabetes
The freezer is where they ideally should be anyway
If reactions are bothersome, trying a single dose of cetirizine or loratadine 30 to 60 minutes before injection is a reasonable low-risk strategy
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NICE guidelines emphasise that GLP-1 therapy should be part of a comprehensive weight management or diabetes care programme
More than 95% of patients are less than 1 year of age at presentation, with about 80% less than 6 months
