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Protocols frequently run for extended periods because tissue and anti-aging effects develop slowly

The primary endpoint was change in HbA 1c (%-points) from baseline to week 68 with CagriSema 2.4 mg/2.4 mg versus semaglutide 2.4 mg

If you suspect your medication is causing side effects, you or your healthcare professional can report these through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or the Yellow Card app)

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Don't panic if your skin feels slightly different early on

The different CRP isoforms, nCRP, non-native pentameric CRP (nnCRP) and mCRP (175178, 181184), may explain their protective and destructive effects, with nCRP being primarily antiinflammatory inducing Th2/M2 responses, while mCRP being typically proinflammatory inducing Th1/M1 responses (170, 185189)