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Additionally, we conducted a Trial Sequential Analysis (TSA) to assess the statistical robustness of the evidence provided by conventional meta-analysis (CMA) for type I or II errors

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We calculated the ROR of the PTs ( n = 92) with no less than 5 reports of psychiatric AEs among treatments with GLP-1 RAs, using the entire FAERS database as a benchmark, and then performed a disproportionality analysis ( Supplementary Figure S1 )

Eligibility is BMI-based (a BMI 35 qualifies on its own