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Semaglutide (Ozempic) is a GLP-1 agonist that reduces appetite and energy intake
Further, to promote sustained weight management, GLP-1 RA users should be educated on healthy diets and physical activity recommendations, and support should be available to encourage long term behaviour change
This was suggested to be accompanied by decreased transcription of urea cycle enzymes, restoration of nitrogen balance, and possible redistribution of nitrogen stores across organs
Keep a symptom diary noting pain location, severity (on a 0-10 scale), timing relative to meals and medication doses, and associated symptoms
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