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& Ode, K
There is no solid evidence that GLP-1 meds cause NAION, and the absolute risk if there even is one is so low it barely registers
The word lipotropic comes from lipo, meaning fat, and tropic, meaning to stimulate or turn
Novo Nordisks semaglutidethe generic name for Ozempic, Wegovy and Rybelsuswas the most prescribed GLP-1 in 2023, making up over 88% of all new prescriptions
The bile acids (BAs), produced in the liver from cholesterol as primary BAs and transformed in the intestine into secondary BAs by the gut microbiota 9 also modulate L-cell GLP-1 secretion by binding to the transmembrane receptor Takeda G-protein coupled Receptor 5 (TGR5) 10 and the nuclear receptor Farnesoid X Receptor (FXR) 11,12
A two-tailed paired t test was used to determine the statistical significance of the differences between the area containing A plaques and the area around it
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