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This approach requires close monitoring to ensure continued efficacy

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Key points Metabolic disorders, such as diabetes mellitus and obesity, can increase the risk of atrial fibrillation (AF)

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14 Clarification of allergy status is particularly important because sulfonamide antibiotics remain first-line treatments for certain infections, including Pneumocystis jirovecii , Toxoplasma gondii and Stenotrophomonas maltophilia