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First, caffeine is a mild diuretic, which means it makes you lose a little extra fluid, so do not count coffee toward your hydration target the way you would water
More than two-thirds of participants experienced noticeable drops in their body weight
(33896531) Phenytoin accumulation, as well as an increased free fraction of phenytoin, may tend to cause phenytoin toxicity
After that peak, side effects decrease even as the dose remains constant
Some have strong clinical evidence behind them
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