Yes, although rare, allergic reactions like rash, itching, or swelling can occur
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Can we really expect that any B12 therapy can be totally standardised
But it also has a thousand other effects, tissue growth, insulin resistance, raising IGF-1 and the risk of acromegaly
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The most important unresolved safety-related research gaps include long-duration exposure, broader dose-response toxicology, sex-specific effects, reproductive and developmental endpoints, hematology, immune monitoring, genotoxicity assessment, and comprehensive off-target profiling across methyltransferase and non-methyltransferase targets