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GLP-1 receptor agonists have known satiety-promoting effects due to central action of the neuropeptide GLP-1 [1], with reduced activation of appetite- and reward-related brain areas in response to food [18]
There are documented case reports of extreme appetite suppression and psychiatric complications requiring GLP-1 discontinuation in people with restrictive eating patterns ( Leziak et al., J Psychiatric Research, 2026 )
Through the BALANCE model, pharmaceutical manufacturers in Indiana like Eli Lily will be able to sell select GLP-1s to Indianas Medicaid
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