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The administration of myricetin to the STZ-Cd rats significantly normalizes the blood glucose level, the activities of carbohydrate metabolic enzymes and renal function markers and insulin dependent protein expression such as GLUT-2, GLUT-4 and IRS-1, suggesting that myricetin remarkably improves carbohydrate metabolism and glucose transport, subsequently enhancing glucose uptake into cells, glucose utilization and renal function in STZ-Cd rats (22)
Retrieved from Shaikh, S., Shaikh, S., Shaikh, S., et al
All of these receptors are expressed by pancreatic cells, where their activation appears to mediate insulin release at low glucose levels and blockage at high levels (219, 220), (see right side of Figure 2)
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