Other serious side effects that require immediate medical intervention include unexplained muscle pain, dark brown urine, signs of increased calcium levels, high blood pressure symptoms, palpitations, low blood sugar, seizures, signs of decreased blood platelet count or anemia, bronchitis symptoms, and signs of dermatitis exfoliative such as rashes or skin peeling
2) Do not apply on broken skin areas such as open wounds
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Epub 2005 Dec 13
In the second pathway, DA is first converted to 3-methoxytyramine (3-MT) by COMT, and then sequentially acted upon by MAO and ALDH to eventually produce HVA (20, 21)