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In developed countries gastrointestinal symptoms are a common reason for attendance to primary care clinics and to hospital outpatients
The CREDENCE clinical trial evaluated the effects of canagliflozin 100 mg daily versus placebo in 4401 patients with T2DM and chronic kidney disease (CKD)
Palmero S, Bottazzi C, Costa M, Leone M, Fugassa E
After the Treatment You can resume normal daily activities immediately
There are three other categories of laxatives: stool softeners or emollients, osmotic laxatives, and stimulants (Muller-Lissner 2013
The clinical trial data is specifically reassuring on this point: across six trials involving approximately 900 participants, glucose levels, insulin levels, and markers of insulin sensitivity remained unchanged from baseline
