Multiple transport mechanisms involved in the intestinal absorption of metformin: impact on the nonlinear absorption kinetics
2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis
Their use is rising rapidly, and with good reason: These medications have been shown to reduce blood sugar, improve fatty liver, GERD, sleep apnea, osteoarthritis, blood pressure, triglycerides, major adverse cardiovascular events, and even show potential benefits for conditions like alcohol use disorder (Mozaffarian et al., 2025
Psychedelics face their own challenges as most remain Schedule I substances, but they offer a cleaner patent landscape with the possibility of broader protection if successful in treating addiction
doi: 10.1016/j.smallrumres.2025.107465 184
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