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Semaglutide hits MASH targets 2.4mg weekly = steatohepatitis (63% vs 34%) & fibrosis (37% vs 22%) at 72w Also weight (10.5%) & non-invasive markers (ELF, stiffness) No new safety signals

In the REDEFINE 2 trial in patients with type 2 diabetes, it achieved 13.7% weight loss and brought 73.5% of patients to HbAc 6.5% ( [141] )

When you are eating less food, you are also getting less water from food sources

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Glucagon-like peptide-1 receptor agonists favorably address all components of metabolic syndrome