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All animals (up to 5 mice per cage) were housed under controlled conditions in ventilated cages, including a 12-h light/dark cycle, temperatures of 22 4 C or 21 2 C, and relative humidity ranges of 50 15% or 3070% at The Jackson Laboratory and Oslo University Hospital Rikshospitalet, respectively

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The use of fermented collagen from pig tissue as well as type II collagen from chicken cartilage make this supplement non-Halal and unsuitable for vegans or vegetarians

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