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Shi, W., Chen, Z., Chen, X., Cao, L., Liu, P., & Sun, S
Jennifer McCauley, a weight management physician at UNC Health, said Medicaid coverage of GLP-1s was incredibly helpful for our patients. Now theyve stopped coverage, so those people are now going back, regaining some of the weight, because theyre unable to obtain these medications, and also are suffering the health consequences of obesity, McCauley told Stateline
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If somebody [asked] me if its safe to treat people who dont have type 2 diabetes [those who] arent living with obesity, but want to lose [22 pounds] because they would feel better I would say, Lets do a clinical trial
Tirzepatide will do ~$45B in global sales this year (2026)
120 Initial investigations into the neuroprotective effects of GLP-1RAs were conducted in diabetic animal models, where subcutaneous administration of liraglutide not only ameliorated hyperglycemia and peripheral insulin resistance, but also restored impaired brain insulin signaling, resulting in reduced tau hyperphosphorylation associated with AD pathology
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