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Think of it this way: GLP-1 therapy opens the door to significant fat reduction, but without attention to muscle preservation, some of what walks out that door is tissue the body cannot easily afford to lose

Twentieth century advances in peptide biochemistry and protein sequencing enabled John Brown to purify the first incretin, named GIP, in the 1970s

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Heres a side-by-side comparison of the common and serious side effects reported for both Zepbound and Mounjaro 3 , 4 : Important Safety Note: Both medications carry a boxed warning about the potential risk of thyroid C-cell tumours, although this has only been observed in animal studies