In contrast, leaky gut, low-grade inflammation, or dysbiosis may impair GLP-1 secretion and function
After applying strict criteria for both efficacy and safety, they identified a small subset of nutraceuticals as promising and safe for clinical consideration
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It should also be noted that these trials predominantly included relatively healthy older participants, as individuals with potential comorbidities such as cardiovascular or renal diseases were often excluded [12, 34]