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Keeping extremities warm with gloves, warm socks, and hats is particularly important, as hands and feet are often most affected by cold sensitivity
The full data are due at a medical meeting and in a peer-reviewed journal later in 2026
In clinical trials, serious adverse effects requiring discontinuation were reported in less than 2% (9,28,29)
Bring your 2- to 4-week log to your clinical visits to ensure that any dose changes are based on actual data, not memory
However, doctors may recommend taking B12 supplements after the age of 50 years as your ability to absorb B12 decreases with age
& Saltmarsh, M
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