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Current protein & peptide science, 17(5), 488496
Autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, lupus, and others are linked with a long-term increased risk of cardiovascular disease
Inhibition of research subjects glutathione S-transferases by bile acids [PMID: 3420615] Laboratory literature summary: Inhibition of research subjects glutathione S-transferases by bile acids
As GEP44 acts directly on muscle tissue, while its effects on islets require concomitant Y1-R antagonism, activation of Y1-R expressed in muscle tissue may ultimately prove to be a critical factor in reducing serum glucose levels, alongside any potential effects on insulin secretion and glucagon release
Could we see similar trials here
complicates the simple "VAT reduction" story: investigators reported that the compound appears to improve adipose tissue quality, including measures of fibrosis and adipocyte morphology, somewhat independently of changes in fat quantity (PMID 33756511)
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