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[16] Reported rates from trials include: Nausea: ~44% Vomiting: ~25% Diarrhea: ~31% Constipation: ~23% Dyspepsia: ~10% These effects reflect slowed gastric motility and are usually mild, but can lead to clinical implications: Dehydration Electrolyte abnormalities ED presentations for poor oral intake
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Endogenous LAC levels range between 8 and 9 g/g wet rodent tissue corresponding to 4045 nmol/g wet tissue as previously reported in the rodent brain [30, 31]
Discordances concentrate in the mixed-GT cohort