It also has better outcomes than gastroparesis [31]
[18] The NHS and NICE have incorporated this evidence into clinical guidance (NG28), recognising GLP-1 receptor agonists as valuable therapeutic options for patients with type 2 diabetes
However, fewer studies have specifically explored the efficacy of GLP-1RAs in preventing WR and inducing WL after bariatric surgery [54,55,56,57]
At the Endocrine Societys 2025 meeting, researchers reported that in 110 men, a 10% weight loss raised the share with normal total and free testosterone from 53% to 77% over 18 months
A meta-analysis of short-term RCTs indicated that adding GLP-1 receptor agonists to SGLT-2 inhibitors increased the risk of hypoglycaemia and treatment discontinuation due to adverse events [6]
Canadian Journal of Diabetes