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Freezing can damage the peptide structure and render the medication ineffective

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We recommend 8 weeks for most patients, followed by a 4-week break before starting another cycle if desired

Short-term GLP-1R/GCGR dual agonism results in normal insulin secretory capacity during hyperglycemic clamp in DIO mice Having assessed insulin sensitivity using the hyperinsulinemic euglycemic clamp, we next sought to examine the impact of cotadutide on insulin secretory capacity and -cell function in response to hyperglycemia