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The inflammatory response is modulated by diet composition, aging, and microglial priming, and exhibits marked sexual dimorphism, with males typically displaying a more pronounced pro-inflammatory response and females showing relative resilience

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It acts as a potent agonist of the ghrelin receptor (GHS-R1a), promoting robust stimulation of endogenous growth hormone (GH) release

Diagnosis of elevated vitamin B12 begins with serum B12 measurement, typically performed as part of routine blood tests or when investigating anaemia, neurological symptoms, or other clinical concerns