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Stronger metabolic changes 2

[18] [19] More precise quantification can be achieved through imaging modalities such as magnetic resonance imaging (MRI) or computed tomography (CT), though these are typically reserved for research settings or specific clinical indications due to cost and, in the case of CT, radiation exposure

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Your clinician will recommend the medication that makes the most sense for your health history, insurance, and goals

Other research highlights: 30% of GLP-1 users tested positive for SIBO or IMO even after accounting for diabetes (5) GLP-1 medicines caused microbiome changes and altered metabolism in mice (6) GLP-1 medicines tested in humans only had noticeable microbiome changes by 48 weeks (7) Despite not necessarily having slower gut motility, one study found that 88.9% of obese patients had SIBO (8) A meta analysis of people with IBS symptoms, found that up to 78% of people had SIBO, many of whom were undiagnosed (9) Overall, Sun and colleagues (1) could not prove a mechanistic link between GLP-1 medications and SIBO, however they did find that SIBO was twice as likely in GLP-1 users

Implementing these strategies into clinical practice could help improve outcomes and enhance patient survival and quality of life