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Insurers continue to cover costly prescriptions, but do not see long-term benefits
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This is the rationale for using vasodilator drugs such as phosphodiesterase (PDE) III inhibitors, papaverine, and pentoxifylline or micronutrients like magnesium (Mg 2+ ) which seem to have protective effects in the noise-exposed cochlea (Figure 2)
However, the most favorable effects on bone mineral density and microarchitecture were noted at concentrations much higher than those approved for human obesity treatment
Clinical research highlights its ability to promote fibroblast activation, enhance angiogenesis, and modulate gene expression associated with youthful cellular function
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