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Philp D et al

The FDA's draft guidance on obesity drug trials recommends monitoring for this in women [8]

Diabetes Care, 1997, Vol 20(3), pp 244247

2018: A double-blind, placebo-controlled study among women receiving taxane-based chemotherapy to treat breast cancer found that 3 grams of acetyl-L-carnitine taken daily for 5.5 months significantly WORSENED symptoms of chemotherapy-induced peripheral neuropathy compared to placebo, and this difference persisted after 2 years [7][28]

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L-carnitine is also used in treating heart disease, including irregular heartbeat, myocardial infarction (cardiomyopathy), angina, and ischemia [15]