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The DREAMS-3 trial put mazdutide directly against semaglutide in a head-to-head comparison

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Notably, ILC2 proportions were comparable between IL-33 alone and IL-33 plus melatonin and Luzindole groups ( Figures 2K, L ), yet BALF concentrations of IL-5 ( Figures 2M ) and IL-13 ( Figures 2N ) remained significantly reduced with melatonin treatment, again indicating dampened ILC2 activity rather than altered ILC2 abundance

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Current Neuropharmacology , 16(5), 566-583

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