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CagriSema is two separate moleculessemaglutide (GLP-1 agonist) plus cagrilintide (amylin analog)combined in one injection

Sestrins activate Nrf2 by promoting p62-dependent autophagic degradation of Keap1 and prevent oxidative liver damage

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Hemolysis assay The various concentrations of D-CuP solution or hydrogel extract (G or G/D-CuP) (500 L) and 2% (v/v) red blood cells (RBC) suspension (500 L) were added to a 1.5 mL tube as sample groups

The membrane was then incubated overnight at 4C with primary antibodies against AKT (1:1000), P-AKT (1:1000), STAT3 (1:1000), P-STAT3 (1:1000), and GAPDH (1:1000)